Date of Award

2016

Publisher

North Dakota State University

Document Type

Thesis

Degree Awarded

Master of Science (MS)

Program

Electrical and Computer Engineering

Department

Electrical and Computer Engineering

College

Engineering

Faculty Advisor

Nawarathna, Dharmakeerthi

Description

The objective of this study was to investigate the effects of electrical stimulation on the cellular chemistry and proliferation of C2C12 muscle cell line. The cells were cultured under the condition of AC electrical stimulation using interdigitated electrode arrays. This research was conducted by applying electrical signals for up to 24 hours to C2C12 muscle cells. After 24 hours, the electrical impedance, cell morphology, proliferation and viability were recorded. The results demonstrated that electrical stimulation have a positive impact on the cell growth of C2C12. These results obtained would aid in future study on improving the techniques of culturing C2C12 muscle cells and also in the field of electrical conductivity in cell proliferation. Lastly, the results obtained also would provide essential information to the studies related to gene and protein expression of cellular and subcellular components after being exposed to electrical stimulation.

Rights

NDSU Policy 190.6.2

Rights Link

https://www.ndsu.edu/fileadmin/policy/190.pdf

Author ORCID Identifier

0000-0001-6103-3250

Handle Identifier

https://hdl.handle.net/10365/28058

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