Date of Award
2012
Publisher
North Dakota State University
Document Type
Master's Paper
Degree Awarded
Master of Science (MS)
Department
Microbiological Sciences
College
Agriculture, Food Systems and Natural Resources
Faculty Advisor
Gibbs, Penelope
Description
Study 1: HIV patients with chronic HBV and/or HCV are more likely to die of liver disease and have a more rapid progression to Acquired Immunodeficiency Syndrome (AIDS) than patients solely infected with HIV. Blood samples were assayed for the presence of HIV 1/2 antibodies, Hepatitis B Surface Antigen (HBsAg) and Hepatitis C antibodies (HCVab). The prevalence of HBV and HCV among HIV patients was 13% and 10%, respectively. This calls for integration of HBV and HCV prevention, and treatment into HIV programs. Study 2: The current techniques used to diagnose EPM have low sensitivities and some are expensive. To improve serologic diagnosis of EPM, a trivalent antigen (rSAG2/4D1/3D2) was expressed, purified and later incorporated into indirect ELISAs. rSAG2 and rSAG4D1/3D2 reported two and one false negative (s), respectively while rSAG2/4D1/3D2 reported none at a cut off of 15% positivity. rSAG2/4D1/3D2 could be more accurate and reliable than rSAG2 and rSAG4D1/3D2.
Recommended Citation
Kyomuhangi, Annet, "Hepatitis Virus B and Hepatitis Virus C Co-Infection Among HIV Patients and Development of an Enzyme Linked Immunosorbent Assay (ELISA) for Diagnosis of Equine Protozoa Myeloencephalitis" (2012). Microbiological Sciences. 12.
https://digitalcommons.ndsu.edu/microbiological-sci/12
Rights
NDSU policy 190.6.2
Rights Link
https://www.ndsu.edu/fileadmin/policy/190.pdf
Handle Identifier
https://hdl.handle.net/10365/22229